Medicated chewing gum

Skyepharma’s medicated chewing gum is suitable for either local delivery of drugs through the buccal mucosa or for use where systemic delivery can be improved by the active drug being solubilised in saliva prior to swallowing.

How Skyepharma’s medicated chewing gum works

Skyepharma’s proprietary medicated chewing gum technology uses an approach similar to multilayer tableting. A combination of layers modulates the release rate of the active ingredients and flavouring agents when the gum is chewed. The active drug is released into the salvia for either local or systemic effect.

Benefits of Skyepharma’s medicated chewing gum technology

Skyepharma’s medicated chewing gum is patient-friendly and offers a convenient and discreet drug delivery solution. It is especially suitable for:

  • Delivery of drugs that are metabolised by the gut wall or the liver, so avoiding the first pass effect whereby drugs are metabolised prior to entering the systemic circulation. This allows more rapid delivery and better bioavailability of the drug and therefore the use of lower doses.
  • Bioavailability enhancement for poorly soluble drugs by facilitating their solubilisation in saliva before swallowing
  • Local buccal treatment by prolonging contact between the drug and the highly vascularised oral mucosa

> Other oral bioavailability enhancers

Contact us to find out how we can help with your oral drug delivery project.

Copyright 2014, Skyepharma. All Rights Reserved. Skyepharma PLC is a public limited company registered in England and Wales, registration number 0107582.
Registered office: 46-48 Grosvenor Gardens, London SW1W 0EB, United Kingdom

Contact addresses

Skyepharma PLC
46-48 Grosvenor Gardens

Tel: +44 207 881 0524

Fax: +44 207 881 1199

E-mail us

Skyepharma AG
Eptingerstrasse 61
4132 Muttenz

Tel: +41 61 467 5555

Fax: +41 61 467 5500

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